The Japanese Red and Green have one of the oddest glitches ever: if you evolve your starter before getting the Pokédex, you can't get the Pokédex at all, meaning you can't get Pokéballs either, and as a result you can't get past Viridian City. The one question I have is, how the hell does that work?
Another odd Japan-only glitch, which is reportedly only in very early copies of the game, is that when you go to the second floor of the Pokémon League's Pokémon Center, you can't get back down because of a glitch. And guess what? If you have any business at all there, odds are you WILL be saving there. Meaning you're permanently stuck. BRILLIANT.
So next time you get mad at the localization teams for taking their sweet time, remember that all those bugs are usually weeded out in the process, which will make things much less frustrating in the long run.